Ibisobanuro
Ibi birashobora kugerwaho hifashishijwe uburyo butandukanye, harimo kwibasira inzira yihariye ya biohimiki, guhindura ibisubizo byumubiri, cyangwa kwica cyangwa kubuza gukura kwa virusi. Kimwe mu bintu by'ingenzi byifashishwa mu kuvura imiti neza ni ugusobanukirwa neza ubwoko bw’inyamaswa zivurwa. Ubwoko butandukanye burashobora kugira itandukaniro rinini rya anatomique, physiologique, na metabolike bigira ingaruka kumiti, gukwirakwiza, metabolism, no gusohoka. Kurugero, gastrointestinal pH, ibikorwa bya enzyme, nibikorwa byimpyiko biratandukanye mubinyabuzima, bigira ingaruka kumiti ya farumasi no gukora neza. Byongeye kandi, ibintu nkimyaka nuburinganire nabyo birashobora kugira ingaruka kumiti ya metabolisme, kandi dosiye cyangwa inshuro nyinshi birashobora guhinduka. Byongeye kandi, indwara yihariye ivurwa ninzira yayo y’indwara igomba kwitabwaho muguhitamo imiti ikwiye. Indwara ya etiologiya, pathogenez, hamwe nubuvuzi bwindwara ziratandukanye. Gusobanukirwa nuburyo bwindwara nibyingenzi muguhitamo imiti yibasira virusi cyangwa ikemura ibibazo byihariye. Byongeye kandi, hakwiye gusuzumwa icyiciro cyindwara, ubukana, nubunini bwangirika bwimitsi kugirango harebwe uburyo bwiza bwo kuvura. Gutegura ibiyobyabwenge, harimo nuburyo bwa dosiye, nabyo bigira uruhare runini. Ifishi itandukanye ya dosiye, nkibinini byo munwa, ibisubizo byinshinge cyangwa amavuta yo kwisiga, bifite bioavailable zitandukanye hamwe na profili ya farumasi. Ibintu nkibisubizo byibiyobyabwenge, ituze, ninzira igenewe ubuyobozi bigomba gutekerezwa muguhitamo ifishi ikwiye.
Umubare ninzira yubuyobozi nibyingenzi kugirango ugere ku ngaruka zo kuvura no kwirinda ingaruka mbi. Igipimo kigomba kugenwa ukurikije ibintu nkubwoko bwinyamaswa, uburemere bwumubiri, imyaka, ubukana bwindwara, hamwe na farumasi ya farumasi na farumasi. Byongeye kandi, inzira y'ubuyobozi igomba gutoranywa hashingiwe ku bintu nko gutangira ibikorwa byifuzwa, kwinjiza ibiyobyabwenge no kubiranga, ndetse n'imiterere y'inyamaswa. Muri make, gukoresha ibiyobyabwenge mu kuvura indwara zinyamaswa bisaba gusobanukirwa byimazeyo inyamaswa, indwara, nibiyobyabwenge. Ubu bumenyi bukubiyemo gusuzuma ibintu nkubwoko bwinyamaswa, imyaka, igitsina, ubwoko bwindwara na patologiya, imiterere ya dosiye, igipimo, n'inzira y'ubuyobozi.
Ipaki: Buri gice gifite umufuka wa poly, ibice 200 hamwe na karito yohereza hanze.